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Colony History: Hla®(SD)CVF®

Complete viral antibody profiles, gross pathology profiles, bacteriology profiles, growth charts, and blood chemistries are available for this strain.

The colony history began with a colony of rats established by Robert Dawley around 1925. SD rats are often referred to as "Spargue-Dawley®" Mr. Dawley used both his name and the maiden name, "Sprague", of his wife to create the name of the stock. The colony then went to Sprague Dawley, Inc. in 1945. NIH began a closed colony with animals obtained from Sprague Dawley, Inc.

Hilltop Lab Animals, Inc. received animals from NIH in 1984. Through cesarean rederivation, the animals were
fostered onto gnotobiotic rats in isloation. Descendents of these animals then became the colonies currently available.

All colony histories contain some possiblity of inaccuracy. This information is being provided to the best of Hilltop's knowledge.

The coat color of the rat is albino. The rat is propagated using an outbred breeding system. The colonies, located at Hilltop Lab Animals, Inc., are closed colonies and have been so since 1985. Closed colonies do develop qualities causing the rats to be uniquely suited to certain types of research.

CVF® and Hla® are the registered trademarks of Hilltop Lab Animals, Inc., Scottdale, Pennsylvania.

Sprague-Dawley® is the registered trademark of Harlan Sprague Dawley, Indianapolis, Indiana.